Demethylation of H3K9 and H3K27 Contributes to the Tubular Renal Damage Triggered by Endoplasmic Reticulum Stress

Loss of protein homeostasis (proteostasis) in the endoplasmic reticulum (ER) activates the unfolded protein response (UPR), restoring correct protein folding. Sustained ER stress exacerbates activation of the major UPR branches (IRE1α/XBP1, PERK/ATF4, ATF6), inducing expression of numerous genes inv...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Paula Diaz-Bulnes, Maria Laura Saiz, Viviana Corte-Iglesias, Raúl R Rodrigues-Diez, Aida Bernardo Florez, Cristian Ruiz Bernet, Cristina Martin Martin, Marta Ruiz-Ortega, Beatriz Suarez-Alvarez, Carlos López-Larrea
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-07-01
Serie:	Antioxidants
Soggetti:	ER stress epigenetic modifications histone methylation UPR
Accesso online:	https://www.mdpi.com/2076-3921/11/7/1355
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!