Critical dysregulated signaling pathways in drug resistance: highlighting the repositioning of mebendazole for cancer therapy

BackgroundCancer drug resistance significantly reduces the effectiveness of current anticancer treatments. Multiple dysregulated signaling pathways drive cancer initiation, progression, and related drug resistance. This highlights the need for developing new multi-targeting drugs that are more cost-...

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Principais autores:	Amin Aliabadi, Seyed Zachariah Moradi, Sadaf Abdian, Sajad Fakhri, Javier Echeverría
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2025-07-01
סדרה:	Frontiers in Pharmacology
נושאים:	mebendazole cancer drug resistance drug repositioning angiogenesis apoptosis signaling pathways
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1631419/full
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