ERα down-regulation plays a key role in silibinin-induced autophagy and apoptosis in human breast cancer MCF-7 cells

The estrogen receptor alpha (ERα) has been proven to be one of the most important therapeutic targets in breast cancer over the last 30 years. Previous studies pointed out that a natural flavonoid, silibinin, induced apoptosis in human breast cancer MCF-7 cells. In the present study we report that e...

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Autori principali:	Nan Zheng, Ping Zhang, Huai Huang, Weiwei Liu, Toshihiko Hayashi, Linghe Zang, Ye Zhang, Lu Liu, Mingyu Xia, Shin-ichi Tashiro, Satoshi Onodera, Takashi Ikejima
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2015-07-01
Serie:	Journal of Pharmacological Sciences
Soggetti:	Silibinin Estrogen receptor alpha (ERα) MPP dihydrochloride hydrate (MPP) Apoptosis Autophagy
Accesso online:	http://www.sciencedirect.com/science/article/pii/S1347861315000894
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