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Fibromodulin-overexpressing fibroblast cells increase wound contraction, improve scar quality and enhance angiogenesis: an in-vivo study

Abstract Introduction Fibromodulin, a small leucine rich proteoglycan has been suggested to have prominent role in wound healing. On the other hand, fibroblast cells, due to their ability to secrete growth factors and control inflammation in the wound area, have been proposed as effective approaches...

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Principais autores: Negar Abdollahzadeh, Mehran Vatanchian, Fatemeh Oroojalian, Seyed Ehsan Enderami, Amir Amani, Reza Salarinia
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-05-01
Serier:BMC Biotechnology
Fag:
Fibroblast
Cell isolation
Primary culture
Wound healing
Fibromodulin
Online adgang:https://doi.org/10.1186/s12896-025-00975-5
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