Decreased IL-17–producing TH cells as a diagnostic marker for STAT signaling–related primary immunodeficiencies

Background: Certain primary immunodeficiencies present with decreased TH17 counts, including signal transducer and activator of transcription 3 (STAT3)- and dedicator of cytokinesis 8 (DOCK8)-linked hyper-IgE syndrome (HIES) and STAT1-linked chronic mucocutaneous candidiasis disease (CMCD). The diag...

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Autors principals:	Emese Molnár, MD, PhD, Gábor Kovács, MD, Fariba Tahami, MSc, Hajnalka Andrikovics, MD, PhD, Siobhan Burns, MD, PhD, Sofia Grigoriadou, MD, PhD, Matthew Buckland, MD, PhD, Kimberly Gilmour, PhD
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-03-01
Col·lecció:	Journal of Allergy and Clinical Immunology: Global
Matèries:	IgE TH17 hyper-IgE syndrome STAT1 STAT3 DOCK8
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2772829325002048
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