The association between air pollutant exposure and cerebral small vessel disease imaging markers with modifying effects of PRS-defined genetic susceptibility

Studies have highlighted a possible link between air pollution and cerebral small vessel disease (CSVD) imaging markers. However, the exact association and effects of polygenic risk score (PRS) defined genetic susceptibility remains unclear. This cross-sectional study used data from the UK Biobank....

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Detalhes bibliográficos

Principais autores:	Xiaowei Sun, Shiyang Ma, Yunlu Guo, Caiyang Chen, Lijun Pan, Yidan Cui, Zengai Chen, Rick M. Dijkhuizen, Yan Zhou, Johannes Boltze, Zhangsheng Yu, Peiying Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-08-01
coleção:	Ecotoxicology and Environmental Safety
Assuntos:	Cerebral small vessel disease White matter injury Air pollutant Polygenic risk score Genetic susceptibility
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0147651324007140
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