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Specific nucleotide substitutions in the burst sequence enhance polyhedrin expression in alphabaculoviruses: improvement of baculovirus expression vectors

ABSTRACT Alphabaculoviruses produce a large number of occlusion bodies (OBs) in host cells during the late stage of infection. OBs are mainly composed of the viral product polyhedrin (POLH), and the extremely high-level transcription of the polh gene has been exploited to express foreign proteins in...

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Principais autores: Susumu Katsuma, Koshi Fukaura, Noriko Matsuda-Imai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2025-05-01
coleção:Applied and Environmental Microbiology
Assuntos:
Acesso em linha:https://journals.asm.org/doi/10.1128/aem.00144-25
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