Biochemical analysis reveals aberrant and variable Immunoglobulin M composition in Waldenström macroglobulinemia and IgM monoclonal gammopathy of unknown significance

Waldenström Macroglobulinemia (WM) is a rare B cell malignancy defined by greater than 10% infiltration of lymphoplasmacytic cells in the bone marrow (BM) and a circulating monoclonal Immunoglobulin M (IgM), while its precursor state IgM monoclonal gammopathy of undetermined significance (MGUS) has...

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Главные авторы:	Nienke Oskam, Wouter Verhaar, Pleuni Ooijevaar-de Heer, Karima Amaador, Ninotska I. L. Derksen, Sofie Keijzer, Marie José Kersten, Marij Streutker, Josephine M. I. Vos, Theo Rispens
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2025-11-01
Серии:	Frontiers in Immunology
Предметы:	Waldenström macroglobulinemia MGUS antibodies polymerization paraprotein
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1670408/full
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