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It’s Getting Complicated—A Fresh Look at p53-MDM2-ARF Triangle in Tumorigenesis and Cancer Therapy

Anti-tumorigenic mechanisms mediated by the tumor suppressor p53, upon oncogenic stresses, are our bodies’ greatest weapons to battle against cancer onset and development. Consequently, factors that possess significant p53-regulating activities have been subjects of serious interest from the cancer...

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Auteurs principaux: Che-Pei Kung, Jason D. Weber
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2022-01-01
Collection:Frontiers in Cell and Developmental Biology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fcell.2022.818744/full
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