Inferring an ancestral alginate lyase for improved stability and high-level expression using fed-batch fermentation

Alginate lyases are valuable biocatalysts, but their industrial application is often constrained by limited stability and low production efficiency. In this study, an alginate lyase from Flavobacterium sp. was heterologously expressed in different host systems, among which Escherichia coli exhibited...

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Prif Awduron:	Hongxiao Mu, Renquan Guo, Beichen Zhao, Zhuang Huang, Mingda Lei, Lei Lei, Jun Liu, Xing Wang, Zhenggang Xie
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Frontiers Media S.A. 2026-03-01
Cyfres:	Frontiers in Microbiology
Pynciau:	alginate lyase ancestral sequence inferring fed-batch fermentation heterologous expression pH and thermal stability
Mynediad Ar-lein:	https://www.frontiersin.org/articles/10.3389/fmicb.2026.1799015/full
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!