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Experimental assessment of AI-based interactome mapping

Abstract Genotype-phenotype relationships are mediated through intricate networks of physical and functional interactions among macromolecules. Knowledge of the interactome is vital to understand and model genetics and cellular biology. Recent advances in accurately predicting tertiary protein struc...

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Autors principals: Luke Lambourne, Anupama Yadav, Yang Wang, Alice Desbuleux, Dae-Kyum Kim, Florent Laval, Kerstin Spirohn-Fitzgerald, Tiziana Cafarelli, Carles Pons, István A. Kovács, Noor Jailkhani, Sadie Schlabach, David De Ridder, Katja Luck, Vladimir V. Botchkarev, Olivia Debnath, Wenting Bian, Yun Shen, Zhipeng Yang, Miles W. Mee, Mohamed Helmy, Yves Jacob, Irma Lemmens, Thomas Rolland, Gregory G. McClain, Atina G. Coté, Marinella Gebbia, Nishka Kishore, Jennifer J. Knapp, Joseph C. Mellor, Gonen Memisoglu, Jüri Reimand, Jan Tavernier, Michael E. Cusick, Quan Zhong, Patrick Aloy, Tong Hao, Benoit Charloteaux, Frederick P. Roth, Javier De Las Rivas, Pascal Falter-Braun, David E. Hill, Michael A. Calderwood, Jean-Claude Twizere, Marc Vidal
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2026-04-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-026-70942-x
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