Genome-Guided Discovery of Natural Products through Multiplexed Low-Coverage Whole-Genome Sequencing of Soil Actinomycetes on Oxford Nanopore Flongle

ABSTRACT Genome mining is an important tool for discovery of new natural products; however, the number of publicly available genomes for natural product-rich microbes such as actinomycetes, relative to human pathogens with smaller genomes, is small. To obtain contiguous DNA assemblies and identify l...

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Autori principali:	Rahim Rajwani, Shannon I. Ohlemacher, Gengxiang Zhao, Hong-Bing Liu, Carole A. Bewley
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2021-12-01
Serie:	mSystems
Soggetti:	actinomycetes bioinformatics biosynthetic gene cluster cyclic dipeptide genomics glycopeptide
Accesso online:	https://journals.asm.org/doi/10.1128/mSystems.01020-21
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