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Paraventricular Hypothalamic Mechanisms of Chronic Stress Adaptation

The hypothalamic paraventricular nucleus (PVN) is the primary driver of hypothalamo-pituitary-adrenocortical responses. At least part of the role of the PVN is managing the demands of chronic stress exposure. With repeated exposure to stress, hypophysiotrophic corticotropin-releasing hormone (CRH) n...

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Autors principals: James P Herman, Jeffrey Tasker
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016-10-01
Col·lecció:Frontiers in Endocrinology
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Accés en línia:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00137/full
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