Unstabilized DNA breaks in HTLV-1 Tax expressing cells correlate with functional targeting of Ku80, not PKcs, XRCC4, or H2AX

<p>Abstract</p> <p>Background</p> <p>Expression of the human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein rapidily induces a significant increase of micronuclei (MN) and unstabilized DNA breaks in cells. Unstabilized DNA breaks can have free 3′-OH ends accessible to <it>in situ</it> additio...

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Váldodahkkit:	Majone Franca, Jeang Kuan-Teh
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMC 2012-04-01
Ráidu:	Cell & Bioscience
Fáttát:	HTLV-1 Tax Ku80 PKcs XRCC4 H2AX DNA damage
Liŋkkat:	http://www.cellandbioscience.com/content/2/1/15
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