Adaptive responses of genome-reduced Bacillus subtilis during enzyme secretion in a breathing vessel culture

Abstract Background The utilisation of microbes for the production of enzymes and pharmaceutical proteins is an important step towards a sustainable future. However, the energy requirement for agitation, aeration and cooling during industrial fermentation processes is substantial. To address this ch...

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Hlavní autoři:	Ayşegül Öktem, Kyosuke Yokoyama, Yuzheng Wu, Francesca Grilli, Sandra Maaß, Shu Ishikawa, Masato Yotsuya, Ryosuke Sato, Jan Maarten van Dijl, Ken-ichi Yoshida
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-01-01
Edice:	Microbial Cell Factories
Témata:	Bacillus subtilis ‘breathing’ fermenter Industrial enzyme production Proteomics Genome reduction Stress response
On-line přístup:	https://doi.org/10.1186/s12934-026-02942-x
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