Prodrug nanoassembly technology for colorectal cancer therapy
The clinical efficacy of Irinotecan is constrained by individual variability in its enzymatic conversion to the active metabolite, SN38. While direct administration of SN38 bypasses this enzymatic process and demonstrates potent anti-tumor activity, its clinical application remains hindered by poor...
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| Hauptverfasser: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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KeAi Communications Co., Ltd.
2025-12-01
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| Schriftenreihe: | Biomedical Technology |
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| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S2949723X25000467 |
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