Fecal Microbiome Transplantation from Children with Autism Spectrum Disorder Modulates Tryptophan and Serotonergic Synapse Metabolism and Induces Altered Behaviors in Germ-Free Mice

ABSTRACT To determine the relationship of the gut microbiota and its metabolites with autism spectrum disorder (ASD)-like behaviors and preliminarily explore the potential molecular mechanisms, the fecal microbiota from donors with ASD and typically developing (TD) donors were transferred into germ-...

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Autori principali:	Lu Xiao, Junyan Yan, Ting Yang, Jiang Zhu, Tingyu Li, Hong Wei, Jie Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2021-04-01
Serie:	mSystems
Soggetti:	fecal microbiota transplantation (FMT) autism spectrum disorder (ASD) gut microbiota tryptophan metabolism serotonin metabolism
Accesso online:	https://journals.asm.org/doi/10.1128/msystems.01343-20
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