Development of an in vivo RNAi protocol to investigate gene function in the filarial nematode, Brugia malayi.
Our ability to control diseases caused by parasitic nematodes is constrained by a limited portfolio of effective drugs and a paucity of robust tools to investigate parasitic nematode biology. RNA interference (RNAi) is a reverse-genetics tool with great potential to identify novel drug targets and i...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2010-12-01
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| Serier: | PLoS Pathogens |
| Online adgang: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1001239&type=printable |
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