Antinuclear antibody targets in autoimmune hepatitis and drug-induced liver injury: Diagnostic relevance of nucleosome antibodies

Background & Aims: Anti-nuclear antibodies (ANA) are detected in 70–100 % of patients with autoimmune hepatitis (AIH) and in 22–33 % of patients with drug-induced liver injury (DILI). However, little is known about the specific antigens which they bind to. This study aimed to investigate the ant...

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Autors principals:	Mirjam Kolev, Michèle Freiburghaus, Guido Stirnimann, Henning Nilius, Martin Wartenberg, Juliette Schlatter, Michael Nagler, Michael P. Horn, Nasser Semmo
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-06-01
Col·lecció:	Journal of Translational Autoimmunity
Matèries:	Autoimmune hepatitis Drug-induced liver injury Anti-nuclear antibodies Anti-nucleosome antibodies Anti-histone antibodies
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2589909026000079
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