Targeting metalloptosis in tumor therapy: from molecular mechanisms to application of metal nanoparticles

Abstract Metal ions-based regulated cell death (RCD), a form of cell death involving metal ions and controlled by one or more cascade signaling pathways, has recently been termed “metalloptosis”. Given the rapid advances in understanding metalloptosis in malignant progression and nanotherapeutics, t...

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Bibliografische Detailangaben

Hauptverfasser:	Jinxiang Wang, Qin Tian, Yuchen Liu, Chao-Yun Cai, Shuying Fu, Jia Li, Yupeng Guan, Xuankai Liao, Danting Su, Tuanwei Sun, Yong Zhang, Rubing Lin, Yuzhi Xu, Jun Pang, Leli Zeng, Yihang Pan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-10-01
Schriftenreihe:	Molecular Cancer
Schlagworte:	Metalloptosis Regulated cell death Metal nanoparticles (MNPs) Cancer therapy Nanomedicine Drug resistance
Online-Zugang:	https://doi.org/10.1186/s12943-025-02414-7
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