Comparative analysis of heterologous lactate dehydrogenase expression in Ogataea polymorpha for enhanced L-Lactic acid production

Abstract Lactic acid (LA) is a key platform chemical with broad industrial applications, including biodegradable plastics and pharmaceuticals. While microbial fermentation enables the sustainable production of optically pure L-lactic acid, challenges persist in substrate flexibility and process opti...

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Hlavní autoři:	Aksyniia Tsaruk, Justyna Ruchala, Roksolana Vasylyshyn, Kostyantyn Dmytruk, Andriy Sibirny
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-05-01
Edice:	Journal of Biological Engineering
Témata:	Lactic acid production Metabolic engineering Ogataea polymorpha Heterologous LDH expression Methanol bioconversion
On-line přístup:	https://doi.org/10.1186/s13036-026-00699-w
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