Paracrine signaling of ferroptotic airway epithelium in crystalline silica-induced pulmonary fibrosis augments local fibroblast activation through glycolysis reprogramming

Chronic exposure to crystalline silica (CS) contributes to pulmonary fibrosis. Airway epithelium dysfunction and fibroblast activation have both been recognized as pivotal players, alongside disturbances in ferroptosis and glycolysis reprogramming. However, the mechanisms involved remain unclear. In...

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Prif Awduron:	Qianmin Li, Yi Ling, Yu Ma, Tao Zhang, Youjing Yang, Shasha Tao
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2024-02-01
Cyfres:	Ecotoxicology and Environmental Safety
Pynciau:	Crystalline silica Paracrine signaling Ferroptosis Glycolysis reprogramming AMPK-Glut1 axis
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S0147651324000691
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