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Loss of Fgr41 in Candida albicans attenuates virulence and increases proinflammatory immune responses in a manner that is dependent on β(1,3)-glucan but not dectin-1

ABSTRACT β(1, 3)-glucan is an essential cell wall polysaccharide in the fungal pathogen Candida albicans and is also an important immunogenic epitope for host recognition. This polymer is normally masked from immune recognition by a layer of mannosylated glycoproteins on the outer cell wall, but it...

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Autors principals: Ainsley E. King, Mikayla M. Mangrum, Sarah J. Kauffman, Kaley E. Taylor, Duncan Arnold, Andrew S. Wagner, Todd B. Reynolds
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2026-04-01
Col·lecció:Infection and Immunity
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Accés en línia:https://journals.asm.org/doi/10.1128/iai.00523-25
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