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Sphingolipids as a Culprit of Mitochondrial Dysfunction in Insulin Resistance and Type 2 Diabetes

Insulin resistance is defined as a complex pathological condition of abnormal cellular and metabolic response to insulin. Obesity and consumption of high-fat diet lead to ectopic accumulation of bioactive lipids in insulin-sensitive tissues. Intracellular lipid accumulation is regarded as one of the...

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Bibliografske podrobnosti
Principais autores: Kamila Roszczyc-Owsiejczuk, Piotr Zabielski
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021-03-01
Serija:Frontiers in Endocrinology
Teme:
Online dostop:https://www.frontiersin.org/articles/10.3389/fendo.2021.635175/full
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