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Single Cell Hydrodynamic Stretching and Microsieve Filtration Reveal Genetic, Phenotypic and Treatment-Related Links to Cellular Deformability

Deformability is shown to correlate with the invasiveness and metastasis of cancer cells. Recent studies suggest epithelial-to-mesenchymal transition (EMT) might enable cancer metastasis. However, the correlation of EMT with cancer cell deformability has not been well elucidated. Cellular deformabil...

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Principais autores: Fenfang Li, Igor Cima, Jess Honganh Vo, Min-Han Tan, Claus Dieter Ohl
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-05-01
coleção:Micromachines
Assuntos:
cancer metastasis
deformability
epithelial to mesenchymal transition
TP53 genes
chemotherapy drug
microfluidic hydrodynamic stretching
Acesso em linha:https://www.mdpi.com/2072-666X/11/5/486
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