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Development of Floating-Mucoadhesive Microsphere for Site Specific Release of Metronidazole

Purpose: The purpose of this study was to develop and evaluate metronidazole loadedfloating-mucoadhesive microsphere for sustained drug release at the gastric mucosa.Methods: Alginate gastroretentive microspheres containing metronidazole were preparedby ionic gelation method using sodium bicarbonate...

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Principais autores: Md. Lutful Amin, Tajnin Ahmed, Md. Abdul Mannan
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2016-06-01
coleção:Advanced Pharmaceutical Bulletin
Assuntos:
Alginate
Guar gum
Floating microsphere
Metronidazole
Mucoadhesive microsphere
Eudragit
Acesso em linha:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-195.pdf
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