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Accurate MHC Motif Deconvolution of Immunopeptidomics Data Reveals a Significant Contribution of DRB3, 4 and 5 to the Total DR Immunopeptidome

Mass spectrometry (MS) based immunopeptidomics is used in several biomedical applications including neo-epitope discovery in oncology, next-generation vaccine development and protein-drug immunogenicity assessment. Immunopeptidome data are highly complex given the expression of multiple HLA alleles...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Saghar Kaabinejadian, Carolina Barra, Bruno Alvarez, Hooman Yari, William H. Hildebrand, Morten Nielsen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2022-01-01
Cyfres:Frontiers in Immunology
Pynciau:
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fimmu.2022.835454/full
Tagiau: Ychwanegu Tag
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