The Pharmacological Potential of Adenosine A_2A Receptor Antagonists for Treating Parkinson’s Disease

The adenosine A_2A receptor subtype is recognized as a non-dopaminergic pharmacological target for the treatment of neurodegenerative disorders, notably Parkinson’s disease (PD). The selective A_2A receptor antagonist istradefylline is approved in the US and Japan as an adjunctiv...

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Hauptverfasser:	Akihisa Mori, Jiang-Fan Chen, Shinichi Uchida, Cecile Durlach, Shelby M. King, Peter Jenner
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-04-01
Schriftenreihe:	Molecules
Schlagworte:	adenosine A<sub>2A</sub> receptors G protein coupled receptor istradefylline non-dopaminergic target Parkinson’s disease
Online-Zugang:	https://www.mdpi.com/1420-3049/27/7/2366
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