pTERT C250T mutation: A potential biomarker of poor prognosis in metastatic melanoma

Melanoma is the most aggressive form of skin cancer and the leading cause of death from cutaneous tumors. Several studies have associated alterations in the TERT promoter region (pTERT) with gene overexpression, aggressiveness and poor prognosis of the disease. The aim of this study was to clarify t...

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Auteurs principaux:	Leyla Blanco-García, Yolanda Ruano, Raquel Blanco Martínez-Illescas, Rocío Cubo, Paula Jiménez Sánchez, Víctor J. Sánchez-Arévalo Lobo, Erica Riveiro Falkenbach, Pablo Ortiz Romero, María C. Garrido, José L. Rodríguez Peralto
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2023-08-01
Collection:	Heliyon
Sujets:	Melanoma TERT promoter mutations TERT promoter methylation Circulating free DNA Biomarker
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2405844023061613
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