Intraperitoneal Treatment of Cambinol, a Synthetic SIRT1 and SIRT2 Inhibitory Compound, Exacerbates <i>Brucella abortus</i> 544 Burden in the Spleens of Institute of Cancer Research Mice

Our preliminary data using bone marrow-derived macrophages (BMDMs) collected from ICR mice treated with anti-sirtuin (anti-SIRT) 1 antibody showed that <i>Brucella</i> uptake was significantly attenuated. We then further investigated the effect of an inhibitor of SIRT1/2, cambinol, in the progressio...

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Principais autores:	Alisha Wehdnesday Bernardo Reyes, Tran Xuan Ngoc Huy, Trang Thi Nguyen, Said Abdi Salad, Ched Nicole Turbela Aguilar, Wongi Min, Hu Jang Lee, Suk Kim
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2024-12-01
Series:	Microorganisms
Assuntos:	<i>B. abortus</i> cambinol interleukin 10 splenic bacterial burden sirtuins
Acceso en liña:	https://www.mdpi.com/2076-2607/12/12/2533
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