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Human retinal organoid model of disease-relevant photoreceptor cell death amenable to drug screening

Abstract Dry age-related macular degeneration (AMD) is characterized by the progressive loss of retinal pigment epithelium cells in the macula, leading to photoreceptor degeneration and loss of central vision. Current treatments only modestly delay disease progression, but once photoreceptors are da...

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Bibliografische Detailangaben
Hauptverfasser: Shama Parween, Anthony J. Saviola, Anna C. Howell, Stefanie Varghese, David Ceja Galindo, M. Natalia Vergara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2026-04-01
Schriftenreihe:Cell Death and Disease
Online-Zugang:https://doi.org/10.1038/s41419-026-08724-y
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