A Nanobody-Based Toolset to Monitor and Modify the Mitochondrial GTPase Miro1

The mitochondrial outer membrane (MOM)-anchored GTPase Miro1, is a central player in mitochondrial transport and homeostasis. The dysregulation of Miro1 in amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) suggests that Miro1 may be a potential biomarker or drug target in neuronal dis...

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Bibliografski detalji

Glavni autori:	Funmilayo O. Fagbadebo, Philipp D. Kaiser, Katharina Zittlau, Natascha Bartlick, Teresa R. Wagner, Theresa Froehlich, Grace Jarjour, Stefan Nueske, Armin Scholz, Bjoern Traenkle, Boris Macek, Ulrich Rothbauer
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-03-01
Serija:	Frontiers in Molecular Biosciences
Teme:	Miro1 nanobodies imaging proteomics degron
Online pristup:	https://www.frontiersin.org/articles/10.3389/fmolb.2022.835302/full
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