Correlating rrs and eis promoter mutations in clinical isolates of Mycobacterium tuberculosis with phenotypic susceptibility levels to the second-line injectables

Objective/background: The in vitro drug-susceptibility testing of Mycobacterium tuberculosis reports isolates as resistant or susceptible on the basis of single critical concentrations. It is evident that drug resistance in M. tuberculosis is quite heterogeneous, and involves low level, moderate lev...

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Detalhes bibliográficos

Principais autores:	Priti Kambli, Kanchan Ajbani, Chaitali Nikam, Meeta Sadani, Anjali Shetty, Zarir Udwadia, Sophia B Georghiou, Timothy C Rodwell, Antonino Catanzaro, Camilla Rodrigues
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wolters Kluwer Medknow Publications 2016-01-01
coleção:	International Journal of Mycobacteriology
Assuntos:	Drug-susceptibility testing Extremely drug-resistant tuberculosis Level of resistance Mutations
Acesso em linha:	http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=1;spage=1;epage=6;aulast=Kambli
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