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Retrograde and Anterograde Transport of Lat-Vesicles during the Immunological Synapse Formation: Defining the Finely-Tuned Mechanism

LAT is an important player of the signaling cascade induced by TCR activation. This adapter molecule is present at the plasma membrane of T lymphocytes and more abundantly in intracellular compartments. Upon T cell activation the intracellular pool of LAT is recruited to the immune synapse (IS). We...

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Bibliografische gegevens
Hoofdauteurs: Juan José Saez, Stephanie Dogniaux, Massiullah Shafaq-Zadah, Ludger Johannes, Claire Hivroz, Andrés Ernesto Zucchetti
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2021-02-01
Reeks:Cells
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Online toegang:https://www.mdpi.com/2073-4409/10/2/359
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