Exploration of the mechanism of Lithospermum erythrorhizon oil in treating atopic dermatitis based on network pharmacology and experimental validation of the PI3K-Akt pathway regulation

Objective: This study aimed to explore the molecular mechanisms of Lithospermum erythrorhizon oil in treating atopic dermatitis (AD), with a particular focus on its regulatory effect on the PI3K-Akt signaling pathway. Methods: Utilizing a network pharmacology approach integrated with experimental va...

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Bibliografski detalji

Glavni autori:	Weisheng Hu, Yinlan Wang, Yingjie Zhou, Junbao Shi, Zengyan Li, Xiaoling Jiang, Qinyuan Wu, Changming Zhong, Huilan Weng, Sijie Ouyang, Yuan Jing, Xianxiang Cai, Mingda Ye, Ning Huang
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2025-01-01
Serija:	Heliyon
Teme:	Atopic dermatitis Lithospermum erythrorhizon oil Network pharmacology Experimental validation Molecular mechanism PI3K-Akt signaling pathway
Online pristup:	http://www.sciencedirect.com/science/article/pii/S2405844025000878
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