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Selenized Polymer-Lipid Hybrid Nanoparticles for Oral Delivery of Tripterine with Ameliorative Oral Anti-Enteritis Activity and Bioavailability

The oral delivery of insoluble and enterotoxic drugs has been largely plagued by gastrointestinal irritation, side effects, and limited bioavailability. Tripterine (Tri) ranks as the hotspot of anti-inflammatory research other than inferior water-solubility and biocompatibility. This study was inten...

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Principais autores: Yuehong Ren, Chunli Qi, Shuxian Ruan, Guangshang Cao, Zhiguo Ma, Xingwang Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-03-01
coleção:Pharmaceutics
Assuntos:
tripterine
selenium
polymer-lipid hybrid nanoparticles
bioavailability
enteritis
anti-inflammation
Acesso em linha:https://www.mdpi.com/1999-4923/15/3/821
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