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Genome-wide analysis of human disease alleles reveals that their locations are correlated in paralogous proteins.

The millions of mutations and polymorphisms that occur in human populations are potential predictors of disease, of our reactions to drugs, of predisposition to microbial infections, and of age-related conditions such as impaired brain and cardiovascular functions. However, predicting the phenotypic...

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Hlavní autoři: Mark Yandell, Barry Moore, Fidel Salas, Chris Mungall, Andrew MacBride, Charles White, Martin G Reese
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2008-11-01
Edice:PLoS Computational Biology
On-line přístup:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000218&type=printable
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