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Comprehensive transcriptomic analyses identify KDM genes-related subtypes with different TME infiltrates in gastric cancer

Abstract Histone lysine demethylases (KDMs) have been reported in various malignances, which affect transcriptional regulation of tumor suppressor or oncogenes. However, the relationship between KDMs and formation of tumor microenvironment (TME) in gastric cancer (GC) remain unclear and need to be c...

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Autori principali: Haichao Zhang, Haoran Wang, Li Ye, Suyun Bao, Ruijia Zhang, Ji Che, Wenqin Luo, Cheng Yu, Wei Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2023-05-01
Serie:BMC Cancer
Soggetti:
Gastric cancer
Histone lysine demethylases
Tumor microenvironment
Immune infiltration
Immunotherapy
Chemotherapy
Accesso online:https://doi.org/10.1186/s12885-023-10923-1
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