Xrcc5/KU80 is not required for the survival or activation of prophase-arrested oocytes in primordial follicles
IntroductionThe non-growing, meiotically-arrested oocytes housed within primordial follicles are exquisitely sensitive to genotoxic insults from endogenous and exogenous sources. Even a single DNA double-strand break (DSB) can trigger oocyte apoptosis, which can lead to accelerated depletion of the...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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Frontiers Media S.A.
2023-10-01
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| Serie: | Frontiers in Endocrinology |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1268009/full |
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