Evaluating the Immune Response in Rabbits to an Escalating Dose of mRNA-Based HIV-1 Env Immunogens

Background: The development of an effective HIV-1 vaccine remains a major challenge due to HIV-1’s extraordinary diversity, high mutation rate, and the rarity of broadly neutralizing antibody (bnAb) precursors. To address these challenges, we have previously immunized rabbits with mRNA-LNPs encoding...

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Principais autores:	Shamim Ahmed, Durgadevi Parthasarathy, Tashina C. Picard, Gary R. Matyas, Mangala Rao, Alon Herschhorn
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-11-01
Colecção:	Vaccines
Assuntos:	HIV-1 vaccine antibodies
Acesso em linha:	https://www.mdpi.com/2076-393X/13/11/1161
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