DNA methylation landscape reveals GNAS as a decitabine-responsive marker in patients with acute myeloid leukemia

Background: The demethylation agent decitabine (DAC) is a pivotal non-intensive alternative treatment for acute myeloid leukemia (AML). However, patient responses to DAC are highly variable, and predictive biomarkers are warranted. Herein, the DNA methylation landscape of patients treated with a DAC...

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Principais autores:	Shujiao He, Yan Li, Lei Wang, Yisheng Li, Lu Xu, Diya Cai, Jingfeng Zhou, Li Yu
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2024-03-01
סדרה:	Neoplasia: An International Journal for Oncology Research
נושאים:	Acute myeloid leukemia Prognostic biomarker Decitabine Differentially methylated region DNA methylation sequencing GNAS
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S1476558624000022
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