Glioma-targeted oxaliplatin/ferritin clathrate reversing the immunosuppressive microenvironment through hijacking Fe2+ and boosting Fenton reaction

Abstract Glioma is easy to develop resistance to temozolomide (TMZ). TMZ-resistant glioma secretes interleukin-10 (IL-10) and transforming growth factor-β (TGF-β), recruiting regulatory T cell (Treg) and inhibiting the activity of T cells and natural killer cell (NK cell), subsequently forming an im...

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Auteurs principaux:	Xue Li, Ying Cheng, Zhifu Yang, Qifeng Ji, Menglei Huan, Weiliang Ye, Miao Liu, Bangle Zhang, Daozhou Liu, Siyuan Zhou
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2024-03-01
Collection:	Journal of Nanobiotechnology
Sujets:	Glioma Oxaliplatin Ferritin Ferroptosis Immunosuppression
Accès en ligne:	https://doi.org/10.1186/s12951-024-02376-w
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