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Interaction of lncRNA LENT with DHX36 regulates translation and suppresses autophagy in melanoma

Abstract The melanocyte lineage-determining Microphthalmia-associated transcription factor (MITF) drives proliferation and survival of melanocytic melanoma cells through regulation of both coding genes and long non-coding RNAs (LncRNAs). Here we characterize LINC00520 (hereafter called LncRNA ENhanc...

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Autores principales: Alexandre Haller, Giovanni Gambi, Mattia D’Agostino, Guillaume Davidson, Antonin Lallement, Gabrielle Mengus, Chadia Nahy, Nadia Messaddeq, Guillaume Bec, Angelita Simonetti, Eric Ennifar, Irwin Davidson
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2025-12-01
Colección:Cell Death and Disease
Acceso en línea:https://doi.org/10.1038/s41419-025-08296-3
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