A switch in the mode of Wnt signaling orchestrates the formation of germline stem cell differentiation niche in Drosophila.
Germline stem cell (GSC) self-renewal and differentiation into gametes is regulated by both intrinsic factors in the germ line as well as extrinsic factors from the surrounding somatic niche. dWnt4, in the escort cells of the adult somatic niche promotes GSC differentiation using the canonical β-cat...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2018-01-01
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| Col·lecció: | PLoS Genetics |
| Accés en línia: | http://europepmc.org/articles/PMC5811049?pdf=render |
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