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Molecular mechanism of Danshen injection in treating endometrial fibrosis induced by intrauterine adhesions via the LAMC2-CD44-TGF-β1-SMAD2/3 signaling pathway

IntroductionDanshen injection, derived from the traditional Chinese medicine Salvia miltiorrhiza Bunge, has been clinically validated for its safety and efficacy in treating various gynecological diseases, including endometrial fibrosis caused by Intrauterine Adhesion (IUA). However, its molecular m...

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Principais autores: Sisi Tang, Renzhi Hu, Shuangyan Weng, Mei Luo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-04-01
Serier:Frontiers in Physiology
Fag:
Danshen injection
fibrosis
intrauterine adhesion
molecular mechanism
TGF-β1- SMAD2/3 signaling pathway
Online adgang:https://www.frontiersin.org/articles/10.3389/fphys.2026.1794215/full
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