H3 Relaxin Protects Against Myocardial Injury in Experimental Diabetic Cardiomyopathy by Inhibiting Myocardial Apoptosis, Fibrosis and Inflammation

Background/Aims: Apoptosis, fibrosis and NLRP3 inflammasome activation are involved in the development of diabetic cardiomyopathy (DCM). Human recombinant relaxin-3 (H3 relaxin) is a novel bioactive peptide that inhibits cardiac injury; however, whether H3 relaxin prevents cardiac injury in rats wit...

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主要な著者:	Xiaohui Zhang, Liya Pan, Kelaier Yang, Yu Fu, Yue Liu, Jinyu Chi, Xin Zhang, Siting Hong, Xiao Ma, Xinhua Yin
フォーマット:	Artigo
言語:	Inglês
出版事項:	Cell Physiol Biochem Press GmbH & Co KG 2017-10-01
シリーズ:	Cellular Physiology and Biochemistry
主題:	H3 relaxin Diabetic cardiomyopathy NLRP3 inflammasome Apoptosis Cardiac fibrosis
オンライン･アクセス:	https://www.karger.com/Article/FullText/481843
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