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Population-level neural rejuvenation dynamics in addiction: a computational framework for understanding developmental plasticity reactivation

BackgroundThe neural rejuvenation hypothesis proposes that drugs of abuse reactivate developmental plasticity mechanisms to create abnormally persistent addiction memories. While individual molecular components have been characterized experimentally, the population-level dynamics and their collectiv...

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Principais autores: Mehdi Borjkhani, Hadi Borjkhani, Morteza A. Sharif
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2026-02-01
Series:Frontiers in Computational Neuroscience
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fncom.2026.1753417/full
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