Maturation of Purkinje cell firing properties relies on neurogenesis of excitatory neurons

Preterm infants that suffer cerebellar insults often develop motor disorders and cognitive difficulty. Excitatory granule cells, the most numerous neuron type in the brain, are especially vulnerable and likely instigate disease by impairing the function of their targets, the Purkinje cells. Here, we...

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Autors principals:	Meike E van der Heijden, Elizabeth P Lackey, Ross Perez, Fatma S Ișleyen, Amanda M Brown, Sarah G Donofrio, Tao Lin, Huda Y Zoghbi, Roy V Sillitoe
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2021-09-01
Col·lecció:	eLife
Matèries:	Purkinje cells granule cells cerebellum electrophysiology development behavior
Accés en línia:	https://elifesciences.org/articles/68045
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