Complexity of the inoculum determines the rate of reversion of SIV Gag CD8 T cell mutant virus and outcome of infection.
Escape mutant (EM) virus that evades CD8+ T cell recognition is frequently observed following infection with HIV-1 or SIV. This EM virus is often less replicatively "fit" compared to wild-type (WT) virus, as demonstrated by reversion to WT upon transmission of HIV to a naïve host and the association...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Public Library of Science (PLoS)
2009-04-01
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| Ráidu: | PLoS Pathogens |
| Liŋkkat: | http://europepmc.org/articles/PMC2660429?pdf=render |
| Fáddágilkorat: |
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