Impact of Hypermannosylation on the Structure and Functionality of the ER and the Golgi Complex

Proteins of the secretory pathway undergo glycosylation in the endoplasmic reticulum (ER) and the Golgi apparatus. Altered protein glycosylation can manifest in serious, sometimes fatal malfunctions. We recently showed that mutations in GDP-mannose pyrophosphorylase A (GMPPA) can cause a syndrome ch...

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Detalhes bibliográficos

Principais autores:	Patricia Franzka, Svenja Caren Schüler, Takfarinas Kentache, Robert Storm, Andrea Bock, Istvan Katona, Joachim Weis, Katrin Buder, Christoph Kaether, Christian A. Hübner
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-01-01
Colecção:	Biomedicines
Assuntos:	Golgi network endoplasmic reticulum mannosylation
Acesso em linha:	https://www.mdpi.com/2227-9059/11/1/146
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